Specific compounds present in grapefruit are recognized to inhibit CYP450 3A4 and will boost the bioavailability of swallowed fentanyl (reportedly approximately seventy five% of a dose) and
PecFent is available in two different strengths: a a hundred microgram for each spray bottle and also a four hundred microgram for each spray bottle. Be sure that you use the strength that the doctor has prescribed for you.
Les libellés affichés ci-dessous ne sont que des résumés ou extraits issus des avis rendus par la Commission de la Transparence. Seul l'avis complet de la Fee de la Transparence fait référence. Cet avis est consultable à partir du lien "Avis du jj/mm/aaaa" ou encore sur demande auprès de la HAS plus d'informations dans l'aide.
Should you be pregnant or breast-feeding, Consider you may be Expecting or are planning to have a infant, question your physician or pharmacist for suggestions right before getting this medicine.
The European Medicines Company noted that there was a need for rapidly-performing soreness medicines for breakthrough soreness in individuals with cancer. Determined by available details, the Agency concluded that PecFent’s Positive aspects are greater than its challenges and it may be authorised to be used inside the EU.
PecFent can be a ‘hybrid medication’. This means that it is similar to ‘reference medicines’ containing precisely the same Energetic material, but supplied in another way.
Before you use a new bottle of PecFent you have to get ready it for use. This is referred to as ‘priming’.
Through transfer to fentanyl patches, preceding opioid remedy really should be phased out gradually. If affected individual calls for doses >one hundred mcg/hr, >one patch may very well be utilized; take into account alternate or added therapy if doses >three hundred mcg/hr are required. Substitute patch each and every 72 hr and utilize The brand new patch to a distinct web site; stay away from utilizing the very same space of skin for a few days.
PecFent is really a medication utilized for the administration of click here breakthrough ache in Grownups with cancer who are already obtaining opioid therapy.
Hepatic or renal disease: PecFent need to be made use of with warning as a result of hepatic metabolism and renal excretion of PecFent.
It can be advisable to avoid Alcoholic beverages when getting PecFent, as it can enhance the danger of significant Unwanted side effects like respiratory despair.
Your health practitioner will then allow you to discover the ideal dose to relieve your breakthrough suffering. It is essential to abide by your medical professional’s instructions.
PecFent is utilized for the management of breakthrough ache in people with most cancers that are now acquiring and who will be tolerant to opioid therapy for his or her fundamental persistent most cancers soreness.
PecFent includes fentanyl, a powerful opioid, which functions by binding to the human body's opioid receptors to decrease the perception of suffering.